Glutathione and whitening
In fact, the charming elements glutathione is a particularly effective antioxidant supplement with the functions of capturing free oxygen radicals, restoring melanin and promoting the role of collagen synthesis. Glutathione also can effectively enhance the ability of skin to against sun damage.
Skincare can not be separated from the skin whitening and flexibility. The main factors that directly affect the skin whitening and flexibility can be divided into three aspects: First, free oxygen radicals, melanin, is collagen. Medical research shows that human negative emotions such as stress, the role of anger, fear, etc., will produce too much oxygen free radicals. Roaming of oxygen free radicals in the body, damage to any contact with the cells and tissues, and the role of enzymes in the human body system, resulting in the release of collagenase and elastase, resulting in the loss of skin elasticity, wrinkles and vesicles. Cosmetic elements astaxanthin is absorbed through the gastrointestinal transport with the blood to the body tissues of oxygen free radicals in the cells and between cells in liquid environment, capture, removal, to minimize free radical damage to the skin.
The skin color depends on the melanin content of skin. The root causes of the formation of melanin are tyrosinase. Tyrosine its role within the melanocytes dopa quinone is oxidized to form eumelanin, the formation of melanin to gradually reach the surface of the skin with the skin of normal metabolism, the last and the ageing of the skin with natural peeling. If the skin metabolism is not smooth, it will lead to a lot of pigmentation, and gathered in the local skin color will deepen the formation of spots. Therefore, inhibiting tyrosinase biosynthesis and sunscreen is the key to whitening. Elements glutathione can inhibit the activity of tyrosinase, blocking melanin production, and improve the skin dull. Of course, restore melanin to a colourless state and can not guarantee that from this will no longer generate. Really want to whiten, in addition to tretinoin supplementary elements glutathione can inhibit the formation of melanin composition and effective sun protection.
In the skin whitening, how to make the skin maintaining flexibility becomes a key indispensable problem. The skin dermis contains large amounts of collagen in. It gives the skin strength and can maintain the structure of the skin. The substance intertwining among the collagen is elastic fibres and it makes the skin elastic. The flexibility of collagen and elastic fibres changes under the oxidation impact. At this time, the tissue glutathione can play its role of antioxidant and anti-ageing. It enhances collagen production and plays a wrinkle effect. So, for the one who wants to make the skin naturally white, beautiful and moisture, a rich supply of glutathione is required.
Every day your body is attacked by environmental toxins. They are in our food, water and even in the air. The primary movers to combat this are an antioxidant molecule called glutathione. They are in every cell of your body. They are called a tripeptide, as they are composed of three essential amino acids; cysteine, glutamic acid and glycine.
You hear about antioxidants daily and how they protect us from heart disease, cancer and a myriad of other diseases. While vitamin C is the most talked-about antioxidant in the blood, vitamin E is vital in the cell membranes and lipoproteins. Within the interior of the cell, where the actual damage takes place, glutathione is the most important antioxidant. Glutathione circulates constantly through our body, neutralizing free radicals and removing toxins and waste products from our body.
Free radicals are created when our body goes through its normal metabolic process of converting food for energy to fuel your cells. A free radical is an unstable oxygen-containing molecule with an unpaired electron in its outer orbit. That single electron crashes around inside your cell desperately seeking to grab another electron. If it attaches to one the delicate balance of the cell is damaged. If the cell is damaged severely, or often enough, it will no longer work efficiently, may mutate or even die.
Thus far, scientists have identified two types of destructive free radicals; the hydroxyl and superoxide radicals. Two other types of oxygen-containing molecules, hydrogen peroxide and singlet oxygen, are just as dangerous to us. The human body, fortunately, has its own natural way to deal with all four of these dangerous villains.
The same process that creates free radicals also creates their antidote. The energy-producing process creates the antioxidant enzymes glutathione peroxidase, catalase and superoxide dismutase (SOD). These enzymes attack the free radicals in your cells almost as soon as they are formed. They neutralize the destructive free electrons in the oxygen molecule so they can be eliminated from the body easily.
Glutathione is the most important and abundant antioxidant substance in the body. This powerful and incredible antioxidant is your built-in defence mechanism against the ravaging effects of free radicals. It plays a critical role in the removal of metabolic wastes and locating and eliminating toxic substances. These are things like heavy metals and other environmental poisons. It also helps to keep cell membranes strong as well as transports vital amino acids into the cells.
Glutathione was discovered in 1888, but not until the 1920s and 30s were researchers able to unlock some of its mysteries. In the beginning stages, most of the research was focused on the eye, in particular the lens. This initial research was valuable. Glutathione deficiency is directly attributable to eye problems such as cataracts and macular degeneration. A lack of glutathione can lead to disturbance of your bodys ability to detoxify itself. This can lead to cancer, heart disease, joint problems and serious imbalances in your nervous system, endocrine and immune system.
If you are basically healthy, your bodys metabolic processes maintain a natural redox balance. It will quickly neutralize free radicals with antioxidants. This balance can be disrupted from stress, fighting an infection, inflammation, sick or healing from an injury. Free radicals are also created from unavoidable exterior contaminants: alcohol, ultraviolet light, heavy metals like mercury, air pollution, food additives, pesticides and other environmental poisons. Even though glutathione circulates through your system searching for free radicals and toxic wastes, the balance can tip in favor of the invaders.
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Half of the ³-L-glutamyl-L phthalate cysteine phthalocyanine glycine by its chemical name, the English name is L- Glutathione.
Glutathione is isolated from the yeast in 1888; in 1921, scientists extracted crystallized and conceived its structure; elucidate its chemical structure and synthesis team in 1935, Enzymatic synthesis of glutathione mechanismexplore in 1953; seventies of the last century, further study of the chemical synthesis of glutathione, focused on process improvements; eighties of the last century, due to the development of genetic engineering technology, glutathione supplier began to study the production of glutathione bacteria and(enzyme) production of glutathione immobilized.
The relative molecular weight of glutathione is 307.33, the melting point is 189 to 193 ° C, the crystal was colorless and transparent elongated granular, the isoelectric point is 5.93. It is soluble in water, dilute alcohols, ammonia, and dimethylformamide and not soluble in alcohol, ether and acetone. Glutathione solid is more stable, with water in the air is easily oxidized, and the two molecules also prototype active mercapto glutathione disulfide oxidative condensation, i.e. the oxidized glutathione. Expressed in ionic form, can be seen as the missing electron oxidation (SH compound is weakly acidic, H + SH group to). This reaction is reversible, so glutathione has redox role. Oxidized glutathione (GSH) and reduced glutathione was having a physiological activity can play an important physiological need to restore oxidized glutathione vivo function. Therefore, when extracting glutathione can be added substances in solution which having a strong reducing such as vitamin C, etc. when there is a strongly reducing material can protect glutathione is not easy to be oxidized.
Glutathione in the distribution of plants and animals, glutathione nature is abundant in many plants and animals. Very high levels in the baker’s yeast, wheat germ and animal liver is 100 = 1000mg/100g, 26 = 34mg/100g containing in human blood, with blood containing 58 = 73mg/100g , pig blood containing 10 = 15mg / 100g, tomatoes, pineapple, cucumber, content is also higher (12 = 33mg/100g), sweet potatoes, green bean sprouts, onions, mushrooms, low levels (0.06 = 0.7mg/100g). The glutathione structure containing a reactive sulfhydryl-SH, the easily oxidized deoxidation, the specific structure makes it become the main body radical scavengers. The body metabolism of many free radicals can damage cell membranes, invasion of macromolecules of life, promote aging body and generate induced tumors or atherosclerosis. As a cosmetic raw material, glutathione can scavenge free radicals play a strong protective effect on anti-aging. For example, when cells generate a small amount of H2O2 and glutathione in the role of glutathione peroxidase will reduce H2O2 to H2O, and itself is oxidized to GSSG, GSSG by glutathione in the liver and red blood cells, glutathione under the role of reductase catalytic, accept H reduced to glutathione, a free radical reactions to be sustained. Glutathione is a very special amino acid derivatives, and mercapto group-containing tripeptide, so it plays an important role in vivo.