The Max Difference
Science
Glutathione
RiboCeine
Research Team
Company
Media
The Max Difference

HOW ARE WE DIFFERENT?

Max International is dedicated to improving everyday lives. This commitment can be seen in everything we do, from our superior products to the charity events we organize around the world. This isn’t some newfound mission; it’s been our focus from Day 1.

Thanks to the efforts of medicinal chemist Dr. Herbert T. Nagasawa and other experts in scientific research and development, Max International has developed groundbreaking advances in glutathione enhancing products. Their patented compound RiboCeine has been the subject of over 20 independent peer reviewed studies.

When our founder, Steven Scott, began developing world-class solutions to the ongoing health crises we all face, he started by tapping leading scientists and employees. Our team is committed to safe and effective products that supplement glutathione, the body’s master antioxidant and a vital protector against free radicals. This dedication has earned Max a U.S. patent for RiboCeine™ one of the core components to a variety of our products. We invite you to learn more about our Executive Team, who help guide and drive our initiatives.

Science

Our Science

Max is committed to producing and delivering the best possible glutathione enhancing products in the world. We know how important it is that high quality health and wellness products be based on proven scientific research. Max International is determined to lead the wellness and nutritional industry in delivering quality products based on science and science-based proprietary formulations that support the body in it’s production of Glutathione, one of the body’s super anti-oxidants. Glutathione and its benefits have been the subject of over 100,000 peer reviewed articles on PubMed.com, double that of even Vitamin C.

“We persevered and our experiments finally led to RiboCeine. This was a Eureka moment for me”

Thanks to the efforts of medicinal chemist Dr. Herbert T. Nagasawa and other experts in scientific research and development, Max International has developed groundbreaking advances in glutathione enhancing products. Their patented compound RiboCeine has been the subject of over 20 independent peer reviewed studies.

Independent Studies on RiboCeine – English

Independent Studies on RiboCeine – Simplified Chinese

Independent Studies on RiboCeine – Traditional Chinese

NOTE: The following links take you away from this page to 3rd party research sites. 

1. Saltman A.E.D-Ribose-L-cysteine supplementation enhances wound healing in a rodent model. Am J Surg. 2015, 210, 153-158.

2. Kader, T.; Porteous C.M.; Williams M.A.J.A.; Gieseg, S.P.; McCormick, S.P.A. Ribose-cysteine increases glutathione-based antioxidant status and reduces LDL in human lipoprotein(a) mice. Atherosclerosis. 2014, 237, 725-733.

3. Jurkowska, H.; Uchacz, T.; Roberts, J.; Wrobel, M. Potential therapeutic advantage of ribose-cysteine in the inhibition of astrocytoma cell proliferation Amino Acids, 2011, 41, 131-139.

4. Heman-Ackah, S.E.; Juhn, S.K.; Huang, T.C.; Wiedmann, T.S. Potential therapeutic advantage of ribose-cysteine in the inhibition of astrocytoma cell proliferation Otolaryngology-Head and Neck Surgery, 2010,143, 429-434.

5. Oz, H.S.; Chen, T.S.; Nagasawa, H., Comparative efficacies of 2 cysteine prodrugs and a glutathione delivery agent in a colitis model. Translational Research, , 150(2), 122-129., 150(2), 122-129.

6. Lucas Slitt, A.M.; Dominick, P.K.; Roberts, J.C.; Cohen, S.D. Effect of Ribose Cysteine Pretreatment on Hepatic and Renal Acetaminophen Metabolite Formation and Glutathione Depletion. Basic Clin. Pharmacol. Toxicol., 2005, 96 (6), 487-94.

7. Waldron, C.A.; Vannais, D.B.; Ueno A.M. A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by Ascorbate and Ribs but not DMSO. Mutation Research. 2004, 551-255-265.

8. Lenarczyk, M.; Ueno, A.; Vannais, D.B.; Kraemer, S.; Kronenberg, A.; Roberts, J.C.; Tatsumi, K.; Hei, T.K.; Waldron, C.A. The “Pro-drug” RibCys Decreases the Mutagenicity of High-LET Radiation in Cultured Mammalian Cells.Radiation Research, 2003, 160, 579-583.

9. Wilmore, B.H.; Cassidy, P.B.; Warters, R.L.; Roberts, J.C. Thiazolidine Prodrugs as Protective Agents against y-Radiation-Induced Toxicity and Mutagenesis in V79 Cells. J. Med. Chem., , 44(16), 2661-2666., 44(16), 2661-2666.

10. Lucus, A.M.; Henning G.; Dominick, P.K.; Whiteley, H.E.; Roberts, J.C.; Cohen, S.D. Ribose Cysteine Protects Against Acetaminophen-Induced Hepatic and Renal Toxicity. Toxicologic Pathology, 2000, 28(5), 697-704.

11. Roberts, J.C.; Phaneuf, H.L.; Dominick, P.K.; Wilmore, B.H.; Cassidy, P.B. Biodistribution of [35S] – Cysteine and Cysteine Prodrugs: Potential Impact on Chemoprotection Strategies. J. Labelled Cpd. Radiopharm., 1999all.riboceine.study1.51

12. Roberts, J.C.; Phaneuf, H.L.; Szakacs, J.G.; Zera, R.T.; Lamb, J.G.; Franklin, M.R. Differential Chemoprotection against Acetaminophen-Induced Hepatotoxicity by Latentiated L-Cysteines. Chem. Res. Toxicol., 1998, 11, 1274-1282.

13. Bantseev, V.; Bhardwaj, R.; Rathbun, W.; Nagasawa, H.T.; Trevithick, J.R. Antioxidants and Cataract: (Cataract Induction in Space Environment and Application to Terrestrial Aging Cataract). Biochem. Mol. Bio. Intl., 1997, 42, 1189-1197.

Roberts, J.C.; Koch, K.E.; Detrick, S.R.; Warters, R.L.; Lubec G. 14. Thiazolidine Prodrugs of Cysteamine and Cysteine as Radioprotective Agents. Radiation Research, 1995, 143, 203-213.

15. Carroll, M.P.; Zera, R.T.; Roberts, J.C.; Schlafmann, S.E.; Feeny, D.A.; Johnston, G.R.; West, M.A.; Bubrick, M.P. Efficacy of Radioprotective Agents in Preventing Small and Large Bowel Radiation Injury. Dis. Colon Rectum, 1995, 38(7), 716-722.

16. Roberts, J.C.;Francetic, D.J.; Zera, R.T. Chemoprotection against Cyclophosphamide-Induced Urotoxicity: Comparison of Nine Thiol Protective Agents. AntiCancer Research, 1994, 14, 389-396.

17. Rowe, J.K.; Zera, R.T.; Madoff, R.D.; Fink, A.S.; Roberts, J.C.; Johnston, G.R.; Freeney, D.A.;Young, H.L.; Bubrick, M.P. Protective Effect of RibCys Following High-Dose Irradiation of the Rectosigmoid. Dis. Colon Rectum, 1993, 36(7), 681-687.

18. Roberts, J.C.; Charyulu, R. L.; Zera, R.T.; Nagasawa, H.T. Protection Against Acetaminophen Hepatotoxicity by Ribose-Cysteine (RibCys). Pharmacology & Toxicology, 1992, 70, 281-285.

19. Roberts, J.C.; Francetic, D.J. Mechanisms of Chemoprotection by RibCys, a Thiazolidine Prodrug of L-cysteine. Med. Chem. Res., 1991, 1, 213-219.

20. Roberts, J.C.; Francetic, D.J. Time course for the elevation of glutathione in numerous organs of L1210-bearing CDF1 mice given the L-cysteine prodrug, RibCys. Toxicology Letters, 1991, 59, 245-251.

21. Roberts, J.C.; Francetic, D.J.; Zera, R.T. L-cysteine prodrug protects against cyclophosphamide urotoxicity without compromising therapeutic activity. Cancer Chemotherapy and Pharmacology, 1991, 28, 166-170.

22. Roberts, J.C.; Nagasawa, H.T.; Zera, R.T.; Fricke, R.F.; Goon, D.J. W. Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(polyhydroxyalky)-and 2-(Polyacetoxyalky)-Thiazolidine-4(R)-Carboxylic Acids. . Med Chem., 1987, 30, 1891-1896.

Glutathione

Every day our bodies are challenged by stress, poor diet, lack of sleep and physical exertion. These issues can negatively affect our health and wellness. To help combat these effects, our bodies produce a molecule called glutathione (GSH). 

Glutathione is Fundamental to Our Physical Well-being

 

Glutathione is the primary protector of our cells. It recycles and helps restore other anti-oxidants, earning it the title of Master Antioxidant. It is the first line of defense against our cells’ most violent attackers, namely free radicals, chemical toxins, radiation and heavy metals that enter our bodies through the environment and the foods and liquids we consume. As the subject of over 100,000 peer-reviewed studies cited in PubMed.com, the importance of glutathione cannot be understated.

 

Our Glutathione Levels are Decreasing. Unfortunately, our glutathione levels are depleted as we age. The older we get, the harder it is to maintain optimum glutathione levels. This means our cells don’t work as well and our overall health and wellness pay the price. 

 

Our bodies don’t have to fight on their own. Certain vitamins and nutrients have been shown to assist in glutathione function and production. The key is finding ways to effectively support our bodies’ glutathione levels. Unfortunately, we can’t just take glutathione; we need to find ways to help our bodies produce it naturally. Max’s proprietary RiboCeine™ technology is the solution for effective supplementation for optimal glutathione production.

RiboCeine

RiboCeine™

Scientists and medical doctors have known for decades that glutathione, which is produced by the body itself, is the primary protector and detoxifier of the cell. However, under oxidative stress conditions, the glutathione levels become depleted. Also, from near the age of forty, the body’s ability to produce glutathione decreases gradually, then more rapidly at older age. For years, medical scientists have looked for ways to effectively raise the levels of glutathione. At one time, N-acetylcysteine (NAC) was the only supplement available to enhance the body’s supply of cysteine to enable the production of glutathione. However, Dr. Herbert T. Nagasawa was able to develop a revolutionary molecule known as RiboCeine that effectively delivers cysteine to the cell to support the natural production of glutathione–for which Max International was awarded a U.S. Patent.

  

 

Scientifically Proven and Patented Technology

 

RiboCeine is a unique molecule that combines ribose and cysteine, nutrients that occur naturally in our bodies. RiboCeine once ingested will be absorbed, enters the bloodstream and delivers cysteine and ribose to the cells, supporting glutathione production as well as providing ribose, an integral part of ATP, our cells’ natural fuel and source of energy. RiboCeine significantly outperformed other means of glutathione enhancement against which it has been tested. It has been the subject of twenty- two scientific studies funded by the National Institutes of Health or other scientific funding agencies and published in peer-reviewed journals.

 

Research Team

Max Research & Development Team

Max’s commitment to bring the benefits of Glutathione enhancement to the world starts with our scientific research led by world-renowned medicinal chemist, Dr. Herb Nagasawa and his team.

Dr. Herbert Nagasawa

Dr. Nagasawa, The Father of RiboCeine™

Dr. Nagasawa
Curriculum Vitae

Dr. Nagasawa received his B.S. degree in chemistry from Western Reserve University (now, Case-Western Reserve) in Cleveland, Ohio, and a Ph.D. degree in organic chemistry from the University of Minnesota. Subsequently, he spent two years as a Post-doctoral Fellow in biochemistry at the University of Minnesota before joining the research staff of the V.A. Medical Center in Minneapolis as a Senior Chemist. He was appointed Assistant Professor of Medicinal Chemistry at the University of Minnesota in 1959, and was named Principal Scientist of the VAMC in 1961. He was promoted in 1976 to Senior Research Career Scientist, a nationwide VA title reserved for the VA’s top scientists, and was promoted in 1963 to Associate Professor of Medicinal Chemistry and to Professor in 1973.

 

 

Scott Nagasawa

Scott Nagasawa, Pharm.D., has a successful history as Senior V.P. of Professional Services for a national pharmacy provider and later, was co-owner of regional home infusion pharmacy. Prior to joining Max, he was the Chief Technical Officer for the startup company, Cellgevity, founded by himself, his brother Stuart Nagasawa, M.D., Scott Momii and Dr. Herbert Nagasawa. Together they developed the breakthrough product that is now Max’s premiere supplement. Scott received his Doctor of Pharmacy degree from the University of Southern California (USC). As Director of Pharmaceutical Services for a large teaching hospital in Los Angeles, California, he held the positions of Clinical Instructor of Pharmacy Practice and Adjunct Assistant Professor of Pharmacy Practice at USC.

 

Scott Momii

Scott graduated with a B.A. degree from San Jose State University, received an M.B.A. from Boston University, and completed a summer business program at Sophia University, Tokyo, Japan. Scott has served as both General Manager of a research, development and manufacturing company for specialty chemicals, and as Director of Operations for a biotechnology company that developed vaccines and cancer therapeutics. His responsibilities included manufacturing and quality control, overseeing and implementation of sales and marketing programs, as well as customer service and accounting.

Company

Our Mission:

To empower people to build a legacy of significant change in their lives and the lives of others.

Our Vision:

As the global leader in Glutathione enhancing products we provide the life changing benefits of our patented, science based products to the world.

Our Values:

Our values are based on an uncompromising commitment to integrity.

• We provide only the highest quality scientifically-based health and beauty products.
• Our success is dependent upon effective partnering.
• We believe in the positive impact of entrepreneurship and strive to open its doors to as many people as possible worldwide.
• We recognize, celebrate and reward the successes and achievements of our Max family.
• We value long-term strategies, not short term schemes.
• We value our social responsibility.

We embrace our corporate responsibility to:

• Create products that improve the standard of health
• Generate income opportunities for our partners
• Support philanthropic activities
• All of our actions seek to improve belief and trust in all of our relationships.

One Dream One Vision One Team One Mission

Media

Media

Want to see and hear more about Max’s products, science, and opportunity? Explore our audio and video pages for our exclusive videos and audio files all about Max International. After you’ve watched and listened to them yourself, share with others so they can discover the Max difference for themselves.